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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal GDF5 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
GDF-5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.
BP000072-CYT-442: Recombinant Human Growth Differentiation Factor-5
Source: E. coli-derived.
A homodimer, non-glycosylated, polypeptide chain containing 2 x 120 amino acids and having a total molecular mass of 26.8 kDa.
GDF-5 activity was determined by the induction of alkaline phosphatase activity in ATDC5 cells: EC50 = 4 ug/ml, corresponding to a specific activity of 250 units/mg.
Purity > 98%, by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized without any additives.
Reconstitution: It is recommended to reconstitute the lyophilized Growth Differentiation Factor-5 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other GDF5 Protein:
Recombinant Human Growth Differentiation Factor-5, His Tag
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