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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal GCA Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
GCA, also known as Grancalcin and GCL, is a member of the penta EF hand subfamily which includes sorcin, calpain and ALG2. Grancalcin is highly expressed bone marrow and also can detected in neutrophils and macrophages. Grancalcin interacts with L-plastin which known to have actin bundling activity. It indicates that Grancalcin may play a improtant role in the adhesion of neutrophils to fibronectin. Furthermore, Grancalcin localization is dependent upon calcium and magnesium. It associates with both the granule and membrane fractions which suggested a role for grancalcin in granule-membrane fusion and degranulation.
BP001428-PRO-080: Recombinant Human Grancalcin (GCA) Protein
Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 237 amino acids (1-217.a.) and having a molecular mass of 26.1 kDa. GCA is fused to a 20 amino acid His-tag at N-terminus.
Purity: > 95% by SDS-PAGE.
Formulation: The GCA protein solution (1 ug/ml) is formulated in 20 mM Tris-HCl buffer (pH8.0) 0.1 M NaCl and 20% glycerol.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other GCA Proteins:
Recombinant Human GCA Protein, GST-tagged
Recombinant Human GCA Protein
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