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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal Galectin-3 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Galectin-3 mediates with the alpha-3, beta-1 integrin the stimulation by cspg4 of endothelial cells migration. Galectin-3 plays an necessary part during the acquisition of vasculogenic mimicry and angiogenic properties associated with melanoma progression. LGALS3 overexpression is highly expressed in early stages of papillary carcinoma, and its expression intensity declines during tumor progression. Serum levels of LGALS3 are high in patients with thyroid malignancy but there is considerable overlap in serum LGALS3 concentrations between those with benign and malignant nodular thyroid disease. LGLAS3 takes part as an immune regulator to inhibit T-cell immune responses and promote tumor growth, as a result providing a new mechanism for tumor immune tolerance.
BP000197-CYT-606: Recombinant Human Galectin-3 (Gal-3) Protein
Source: E. coli-derived.
Predicted molecular mass: 26 kDa.
Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2 ug/ml with a peak response obtained at 220 ug/ml.
Purity: > 97% by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized from a concentrated (1 ug/ml) containing 10 mM sodium phosphate buffer, pH-7.5 and 50 mM NaCl.
Reconstitution: It is recommended to reconstitute the lyophilized LGALS3 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other Gal-3 Proteins:
Recombinant Human Galectin-3 Proein, His Tag
Recombinant Human Galectin-3 Proein
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