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Conditions of optimal GADD45A Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Growth arrest and DNA damage-inducible protein GADD45 alpha, also known as DNA damage-inducible transcript 1 protein, DDIT-1, GADD45 and GADD45A, is a member of the GADD45 family. GADD45A can be induced by UV irradiation, X-rays, growth arrest and alkylating agents, of which can be mediated by some kinases other than PKC. GADD45A can interact with MAPK14, GADD45GIP1, PCNA. In T-cells, GADD45A functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity. GADD45A may affect PCNA interaction with some cell division protein kinase complexes, stimulating DNA excision repair in vitro and inhibits entry of cells into S phase.
BP001411-PRO-783: Recombinant Human Growth Arrest and DNA Damage-Inducible Protein GADD45 ? (GADD45A)
Source: E. coli-derived.
Recombinant Human GADD45A protein is a single, non-glycosylated polypeptide chain containing 173 amino acids (1-165 a.a.) and having a molecular mass of 19.4 kDa. Recombinant Human GADD45A protein is fused to 8 amino acids His Tag at C-terminus and purified by proprietary chromatographic techniques.
Purity: > 85.0% by SDS-PAGE.
Formulation: The GADD45A protein solution contains 20 mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.1 M NaCl.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other GADD45A Proteins:
Recombinant Human GADD45A Protein
GADD45A Antibodies:
GADD45A Polyclonal Antibody
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