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Conditions of optimal FZD1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
?rizzled?gene family members encode 7-transmembrane domain proteins which are receptors for Wnt signaling proteins. The FZD1 protein includes a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in the adult heart, placenta, lung, kidney, pancreas, prostate, and ovary and in the fetal lung and kidney.
BP002864-PRO-816: Recombinant Human Frizzled-1 (FZD1) Protein
Source: HEK293 (Human Embryonic Kidney cell line)-derived.
Predicted molecular mass: 46 kDa.
The KD (equilibrium binding constant) of Human FZD1 was measured at less than 10 nM with human Wnt3a as the ligand. The measurements were performed by the ForteBio Octet optical biosensor instrument.
Purity > 95.0% as determined by SDS-PAGE.
Formulation: The protein was lyophilized without any additives.
Reconstitution: It is recommended to reconstitute the lyophilized FZD1 in sterile 1xPBS not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
FZD1 Antibodies:
FZD1 Polyclonal Antibody
FZD1 Polyclonal Antibody
FZD1 Polyclonal Antibody
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