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FSH Protein

Follicle-stimulating hormone

Catalog No. Product Name Size List Price (US$) Quantity
BP000035-HOR-253 Recombinant Human FSH 10 ug 160.00
BP000035-HOR-253 Recombinant Human FSH 1 mg 5200.00
Description

Background
Follicle-stimulating hormone (FSH) is a hormone found in humans and other animals. It is synthesized and secreted by gonadotrophs of the anterior pituitary gland. FSH is a glycoprotein. Each monomeric unit is a protein molecule with a sugar attached to it; two of these make the full, functional protein. The protein dimer contains 2 polypeptide units (1)., labeled alpha and beta subunits. The alpha subunits contain 92 amino acids. The beta subunits vary. FSH has a beta subunit of 118 amino acids (FSH?), which confers its specific biologic action and is responsible for interaction with the FSH-receptor. The sugar part of the hormone is composed of fucose, galactose, mannose, galactosamine, glucosamine, and sialic acid, the latter being critical for its biologic half-life. The half-life of FSH is 3? hours. FSH regulates the development, growth, pubertal maturation, and reproductive processes of the human body.

BP000035-HOR-253: Recombinant FSH Human

Source: HEK293-derived.
A heterodimeric, glycosylated, polypeptide chain transfected with two expression plasmids encoding the human FSH-alpha chain (Accession # P01215) (Met1-Ser116) and human FSH-beta chain(Accession # P01225) (Met1-Glu129) having a total Mw of 38 kDa.
The ED50 as determined by cAMP accumulation in human FSH Receptor transfected Chinese Hamster Ovary cells was found to be 80-450 ug/ml.
Purity > 95%, by SDS-PAGE.
Formulation: Lyophilized from a concentrated (1 ug/ml) solution containing PBS.
Reconstitution: It is recommended to reconstitute the lyophilized Follicle Stimulating Hormone in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other FSH Proteins:
Recombinant Human FSH α/β Protein
Porcine FSH
Human FSH

FSH Antibodies:
FSH Monoclonal Antibody
FSH Monoclonal Antibody
 

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