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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal Fractalkine performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Fractalkine soluble form is chemotactic for t-cells and monocytes, but not for neutrophils. Fractalkine membrane-bound form promotes adhesion of those leukocytes to endothelial cells. Fractalkine regulates leukocyte adhesion and migration processes at the endothelium and binds to CX3CR1. Natural Human Fractalkine is produced as a long protein (373-amino acid) with an extended mucin-like stalk and a chemokine domain on top. The mucin-like stalk permits it to bind to the cell surface. Fractalkine gene is located on human chromosome 16 along with some CC chemokines known as CCL17 and CCL22.
BP000297-CHM-235: Recombinant Human Fractalkine Protein
Source: E. coli-derived.
A single,non-glycosylated, polypeptide chain containing 76 amino acids and having a molecular mass of 8638 Dalton.
The Biological activity is calculated by its ability to chemoattract human T-Lymphocytes using a concentration range of 5.0-10.0 ug/ml corresponding to a Specific Activity of 100,000-200,000 IU/mg.
Purity: > 97% by SDS-PAGE and RP-HPLC.
Formulation: The CX3CL1 was lyophilized from a 0.2 um filtered concentrated (1.0 ug/ml) solution in 20 mM Phosphate buffer, pH 7.4, 50 mM NaCl.
Reconstitution: It is recommended to reconstitute the lyophilized CX3CL1 in sterile 18M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other Fractalkine Proteins:
Recombinant Human Fractalkine Protein, His Tag
Recombinant Rat Fractalkine Protein
Recombinant Human Fractalkine Protein
Fractalkine ELISA Kits:
Human Fractalkine/CX3CL1 ELISA Kit
Mouse Fractalkine/CX3CL1 ELISA Kit
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