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Conditions of optimal Fibronectin Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Plasma fibronectin level is elevated in severe coronary artery disease. Increased plasma fibronectin levels are related with venous thromboembolism (VTE) particularly in males, and extend the probable association between biomarkers and risk factors for arterial atherothrombosis and VTE. Fibronectin plays a role in several cellular processes, including tissue repair, embryogenesis, blood clotting, and cell migration/adhesion. Fibronectin consists in two main forms: 1) as an insoluble glycoprotein dimer that serves as a linker in the etracellular matrix and 2) as a soluble disulphide linked dimer found in the plasma. The plasma form is produced by hepatocytes, and the ECM form is synthesized by fibroblasts, chondrocytes, endothelial cells, macrophages, as well as certain epithelial cells. Fibronectin alos takes part as a general cell adhesion molecule by anchoring cells to collagen or proteoglycan substrates. Fibronectin organizes cellular interaction with the ECM by binding to different components of the extracellular matrix and to membrane-bound Fibronectin receptors on cell surfaces. Molecular Weight 450kDa.
BP000489-PRO-448: Human Fibronectin Protein
Source: Human Plasma-derived.
Predicted molecular mass: 450 kDa.
Purity > 95%, by SDS-PAGE.
Formulation: Lyophilized from a concentrated 1 ug/ml solution containing 0.05 M Tris Cl pH-7.5 and 0.1 M NaCl.
Reconstitution: Purified fibronectin has a tendency to form insoluble aggregates upon reconstitution. We suggest to reconstittue the 1mg Fibronectin with a chaotropic agent such as urea at room temperature at a concentration of 0.2 mg/ml using sterile water.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other Fibronectin Proteins:
Rat Fibronectin Protein
Bovine Fibronectin Protein
Fibronectin Antibodies:
Fibronectin Monoclonal Antibody
Fibronectin Monoclonal Antibody
Fibronectin Monoclonal Antibody
Fibronectin Monoclonal Antibody
Fibronectin 1 Polyclonal Antibody
Fibronectin ELISA Kits:
Rat Fibronectin ELISA Kit
Mouse Fibronectin ELISA Kit
Human Fibronectin ELISA Kit
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