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Conditions of optimal FGFR1OP Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
FGFR1 oncogene partner (FGFR1OP) is a member of the FGFR1OP family. The FGFR1OP protein is an essentially hydrophilic protein proposed to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing the FGFR1OP gene and the FGFR1 gene, is seen in cases of myeloproliferative disorder. The ensuing chimeric protein contains the N-terminal leucine-rich region of the FGFR1OP protein fused to the catalytic domain of FGFR1. The FGFR1OP gene is believed to play a significant role in normal proliferation and differentiation of the erythroid lineage.
BP002536-PKA-031: Recombinant Human FGFR1 Oncogene Partner (FGFR1OP) Protein
Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 403 amino acids (1-379 a.a) and having a molecular mass of 43.5 kDa. FGFR1OP is fused to a 24 amino acid His-tag at N-terminus.
Purity: > 85.0% as determined by SDS-PAGE.
Formulation: FGFR1OP protein solution (1 mg/ml) containing 20 mM Tris-HCl buffer (pH8.0), 10% glycerol and 1 mM DTT.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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