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FGFR1OP Protein

FGFR1 Oncogene Partner, FOP

Catalog No. Product Name Size List Price (US$) Quantity
BP002536-PKA-031 Recombinant Human FGFR1 Oncogene Partner Protein 10 ug 160.00
BP002536-PKA-031 Recombinant Human FGFR1 Oncogene Partner Protein 1 mg 5200.00
Description

Introduction
FGFR1 oncogene partner (FGFR1OP) is a member of the FGFR1OP family. The FGFR1OP protein is an essentially hydrophilic protein proposed to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing the FGFR1OP gene and the FGFR1 gene, is seen in cases of myeloproliferative disorder. The ensuing chimeric protein contains the N-terminal leucine-rich region of the FGFR1OP protein fused to the catalytic domain of FGFR1. The FGFR1OP gene is believed to play a significant role in normal proliferation and differentiation of the erythroid lineage.

BP002536-PKA-031: Recombinant Human FGFR1 Oncogene Partner (FGFR1OP) Protein

Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 403 amino acids (1-379 a.a) and having a molecular mass of 43.5 kDa. FGFR1OP is fused to a 24 amino acid His-tag at N-terminus.
Purity: > 85.0% as determined by SDS-PAGE.
Formulation: FGFR1OP protein solution (1 mg/ml) containing 20 mM Tris-HCl buffer (pH8.0), 10% glycerol and 1 mM DTT.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

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