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FGF 18 Protein

Fibroblast Growth Factor-18, zFGF5, Fgf18, D130055P09Rik

Catalog No. Product Name Size List Price (US$) Quantity
BP002461-CYT-064 Recombinant Mouse Fibroblast Growth Factor-18 Protein 25 ug 160.00
BP002461-CYT-064 Recombinant Mouse Fibroblast Growth Factor-18 Protein 1 mg 2700.00
Description

Introduction
Fibroblast growth factor 18 (FGF18) is a member of the large FGF family which has at least 23 members. FGF18 is a heparin binding growth factor with a core 120 amino acid FGF domain which allows for a common tertiary structure. FGFs are expressed in the course of the embryonic development and in restricted adult tissues. FGF-18 is an indispensable regulator of long bone and calvarial development. FGF-18 signals via FGFR 1c, 2c, 3c, and 4.

BP002461-CYT-064: Recombinant Mouse Fibroblast Growth Factor-18 (FGF 18) Protein

Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 180 amino acids and having a molecular mass of 21 kDa.
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is < 0.5 mg/ml, corresponding to a specific activity of > 2.0?06 units/mg.
Purity: > 95.0% as determined by RP-HPLC and SDS-PAGE.
Formulation: FGF-18 protein was lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
Reconstitution: It is recommended to reconstitute the lyophilized FGF-18 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

FGF18 Antibodies:
FGF18 Polyclonal Antibody

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