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EYA2 Protein

Eyes Absent Homolog 2, EAB1, EC 3.1.3.48

Catalog No. Product Name Size List Price (US$) Quantity
BP002878-PRO-1071 Recombinant Human Eyes Absent Homolog 2 Protein 10 ug 160.00
BP002878-PRO-1071 Recombinant Human Eyes Absent Homolog 2 Protein 1 mg 5200.00
Description

Introduction
EYA2 belongs to tyrosine phosphatase family which specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). EYA2 promotes effective DNA mending by dephosphorylating H2AX, promoting the enlistment of DNA repair complexes having MDC1. EYA2 role as histone phosphatase can explain its part in transcription regulation during organogenesis.

BP002878-PRO-1071: Recombinant Human Eyes Absent Homolog 2 (EYA2) Protein

Source: E. coli-derived.
A single polypeptide chain containing 295 amino acids (244-514) and having a molecular mass of 33.2 kDa. EYA2 is fused to a 24 amino acid His-tag at N-terminus.
Purity: > 90% as determined by SDS-PAGE.
Formulation: The EYA2 solution (0.5 mg/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 0.15 M NaCl, 1 mM DTT and 40% glycerol.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

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