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Conditions of optimal Eotaxin 1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Chemokine (C-C motif) ligand 11 (CCL11) is a small cytokine belonging to the CC chemokine family that is also known as eotaxin. CCL11 selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which CCL11 is a ligand include CCR2, CCR3 and CCR5. The gene for human CCL11 (scya11) is encoded on three exons and is located on chromosome 17.
BP000265-CHM-308: Recombinant Mouse Eotaxin (CCL11)
Source: E. coli-derived.
N-terminal sequence analysis: His-Pro-Gly-Ser-Ile.
Predicted molecular mass: 8403.2 Da.
The Biological activity was determined by measuring the dose dependent phosphorylation of ERK1 and ERK2 in CCR3 transfected 293 cells. Significant ERK phosphorylation is observed with >100 ug/ml (corresponding to a Specific Activity of 10000 IU/mg) of recombinant mouse eotaxin.
Purity > 95%, by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized from a concentrated (1 ug/ml) solution in water containing no additives.
Reconstitution: It is recommended to reconstitute the lyophilized Eotaxin in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other Eotaxin Proteins:
Recombinant Rat Eotaxin (CCL11)
Recombinant Human Eotaxin (CCL11), His Tag
Recombinant Human Eotaxin (CCL11)
Eotaxin ELISA Kits:
Mouse Eotaxin ELISA Kit
Human Eotaxin ELISA Kit
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