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DFFA Protein

DNA Fragmentation Factor Subunit Alpha, DFF-45, Inhibitor of CAD, ICAD, DFF1, DFF45, DNA Fragmentation Factor 45 kDa Subunit

Catalog No. Product Name Size List Price (US$) Quantity
BP001796-PRO-718 Recombinant Human DFFA Protein 25 ug 160.00
BP001796-PRO-718 Recombinant Human DFFA Protein 1 mg 3000.00
Description

Introduction
DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.

BP001796-PRO-718: Recombinant Human DNA Fragmentation Factor Subunit Alpha (DFFA) Protein

Source: E. coli-derived.
A single, non-glycosylated, polypeptide chain containing 351 amino acids (1- 331 a.a.) and having a molecular mass of 38.7 kDa.
Purity: > 90% by SDS-PAGE.
Formulation: The DFFA solution contains 20 mM Tris-HCl buffer (pH 8.0), 10% glycerol and 1 mM DTT.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

Other DFFA Proteins:
Recombinant Human DFFA Protein

DFFA Antibodies:
DFFA Polyclonal Antibody

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