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Conditions of optimal Der P1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
DERP1 is a thiol protease, with a preference for substrates with a large hydrophobic side chain in the P2 position, or with basic residues. DERP1 is a C1 peptidase family member. DERP1 has extensive endopeptidase specificity. DERP1 is N-glycosylated. N-glycanase treatment does not completely remove carbohydrates, suggesting that the protein contains additional glycosylation sites. DERP1 causes an allergic reaction in humans. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis. DERP1 binds to IgE in 80% of patients with house dust allergy.
BP001820-ALR-003: Recombinant Major mite fecal allergen Der p 1 (Der P1) Protein
Source: E. coli-derived.
Recombinant Major mite fecal allergen Der p 1 contains the Dermatophagoides pteronyssinus Der P1 full length protein (a.a. 1-321) and fused to a 6 His Tag at C-terminus, having a total Mw of 34.5 kDa, pI 5.6.
Predicted molecular mass: 34.5 kDa.
Purity: >95% by 10% SDS-PAGE (coomassie staining).
Formulatio: (1 ug/ml) 60 mM NaCl, 50 mM Tris-HCl pH 8.0 and 1.2 M Urea.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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