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Cytokeratin Peptide 7 Antibody

Keratin, type II cytoskeletal 7; Cytokeratin-7; CK-7; K7; Sarcolectin

Catalog No. Product Name Size List Price (US$) Quantity
PA000030-MA1024 Cytokeratin Peptide 7 Monoclonal Antibody 100 ug 350.00
Description

Background

KRT7 is a type II keratin of simple nonkeratinizing epithelia. The deduced 489-amino acid protein has a calculated molecular mass of about 54 kD. K7 contains 4 central alpha-helical segments with heptad repeats of hydrophobic residues characteristic of a coiled-coil region. Within this domain, K7 shares 73% homology with epidermal K6B. KRT7 gene contains 9 exons and spans more than 15.6 kb. K7 gene is mapped to chromosome 12. Keratin 7 is expressed in a wide range of epithelial structures in humans.

PA000030-MA1024: Cytokeratin Peptide 7 Monoclonal Antibody

Mouse Monoclonal Antibody.
Specificity/Sensitivity: Human No cross reactivity with other proteins.
Applications: Western blot: At 1-2?g/ml with the appropriate system to detect cytokeratin peptide 7 in cells and tissues. Immunohistochemistry(P):: At 2-4?g/ml to detect cytokeratin peptide 7 in formalin fixed and paraffin embedded tissues. Immunohistochemistry(F): At 2-4?g/ml to detect cytokeratin peptide 7 in formalin or acetone fixed tissues.
Reactivity: Human.
Immunogen: Cytoskeletal preparation of the RT4human bladder carcinoma cell line.
Purification: Purified by the goat anti-mouse IgG affinity chromatography
Form of Antibody: Lyophilized from 1.2% sodium acetate, with 2 mg BSA and 0.01 mg NaN3 as preservative.
Isotype: Mouse IgG1.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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