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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal CXCL4 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. Oncostatin-A is a member of the CXC chemocinfamily. Human PF4 is used for the proof of heparin-induced thrombocytopenia. Furthermore it is used as an inhibitor in the angiogenesis during tumor therapy.
BP000302-CHM-350: Recombinant Human C-X-C Motif Chemokine Ligand 4 (CXCL4) Protein
Source: E. coli-derived.
N-terminal sequence analysis: Glu-Ala-Glu-Glu-Asp.
Predicted molecular mass: 7.8 kDa.
The ED50 of CXCL4 as determined by its ability to inhibit human FGF basic dependent proliferation of NR6R3T3 mouse fibroblasts was found to be 5-15 ug/ml.
Purity: > 95% by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized after extensive dialysis against 50 mM Tris-HCl pH 8.0 and 150 mM NaCl buffer.
Reconstitution: It is recommended to reconstitute the lyophilized CXCL4 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other CXCL4 Proteins:
Recombinant Human CXCL4 Protein
Human CXCL4 Protein
Recombinant Human CXCL4 Protein
Recombinant Mouse CXCL4 Protein
CXCL4 Antibody:
CXCL4 Polyclonal Antibody
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