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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal I-TAC Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Chemokine (C-X-C motif) ligand 11 (CXCL11) is a small cytokine belonging to the CXC chemokinen family that is also called Interferon-inducible T-cell alpha chemoattractant (I-TAC) and Interferon-gamma-inducible protein 9 (IP-9). It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. Gene expression of CXCL11 is strongly induced by IFNand IFN, and weakly induced by IFN. This chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL10. CXCL11 is chemotactic for activated T cells. Its gene is located on human chromosome 4 along with many other members of the CXC chemokine family.
BP000273-CHM-334: Recombinant Human C-X-C Motif Chemokine 11 (CXCL11) Protein
Source: E. coli-derived.
N-terminal sequence analysis: Phe-Pro-Met-Phe-Lys.
A single, non-glycosylated, polypeptide chain containing 73 amino acids and having a molecular mass of 8300 Dalton.
ED50 range=1-10 ug/ml corresponding to a Specific Activity of 10,000-100,000 IU/mg determined by the dose dependent chemotaxis of human lymphocytes cultured in the presence of IL-2.
Purity: > 95% by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized from a concentrated (1 ug/ml) solution in water containing no additives.
Reconstitution: It is recommended to reconstitute the lyophilized I-TAC in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other CXCL11 Proteins:
Recombinant Human CXCL11 Protein, His Tag
Recombinant Human CXCL11 Protein
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