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Conditions of optimal CLIC4 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Chloride Intracellular Channel Protein 4 (CLIC4) is a 253 amino acid single-pass membrane protein that localizes to both the nucleus and the cytoplasm and contains one GST C-terminal domain. CLIC4 is expressed in various tissues and exhibits an intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells). CLIC4 acts as a monomer which is able to form selective ion channels in target proteins, thus facilitating the transport of chloride and other ions. CLIC4 is believed to have a role in apoptosis and is able to translocate to the nucleus under stress conditions. CLIC4 has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis.
BP001883-PRO-173: Recombinant Human Chloride Intracellular Channel 4 (CLIC4) Protein
Source: E. coli-derived.
Recombinant Human CLIC4 fused with a 20 amino acid His tag at N-terminus is a single, non-glycosylated, polypeptide chain containing 273 amino acids (1-253 a.a.) and having a molecular mass of 30.9 kDa. The CLIC4 is purified by proprietary chromatographic techniques.
Purity: > 95.0% by SDS-PAGE.
Formulation: The CLIC4 solution (0.5 mg/ml) contains 20 mM Tris-HCl buffer (pH8.0), 0.1 M NaCl, 1 mM DTT and 10% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
Other CLIC4 Proteins:
Recombinant Human CLIC4 Protein
CLIC4 Antibodies:
CLIC4 Polyclonal Antibody
CLIC4 Polyclonal Antibody
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