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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal CLIC2 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Chloride Intracellular Channel Protein 2 (CLIC2) is a critical component of all living cells; it regulates cellular traffic of Chloride ion and it can be inserted into membranes anf form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions, channel activity depends on the pH. CLIC2 is involved in regulating membrane potential and organic solute transport. CLIC2 modulates the activity of RYR2 and inhibits Calcium influx. CLIC2 can be detected in the adult brain, liver, lung, heart, stomach, spleen and testis. It is expressed in fetal liver and adult skeletal muscle. CLIC2 is a potential candidate for one of many diseases linked to Xq28.
BP001046-PRO-198: Recombinant Human Chloride Intracellular Channel 2 (CLIC2) Protein
Source: E. coli-derived.
Recombinant Human CLIC2 is a single, non-glycosylated polypeptide chain containing 267 amino acids (1-247 a.a.) and having a molecular mass of 30.5 kDa. CLIC2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Purity: > 95.0% by SDS-PAGE.
Formulation: The CLIC2 solution (1 ug/ml) contains 20 mM Tris-HCl buffer (pH8.0), 20% glycerol 0.1 M NaCl and 1 mM DTT.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
Other CLIC2 Proteins:
Recombinant Human CLIC2 Protein
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