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Conditions of optimal CIRBP Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Cold inducible RNA-binding protein (CIRBP) has a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP localizes to the nucleus and contains one RRM (RNA recognition motif) domain. Expressed ubiquitously, CIRBP is believed to play a crucial role in the suppression of cellular proliferation in response to UV irradiation or extreme cold.
BP001548-PRO-746: Recombinant Human Cold Inducible RNA Binding Protein (CIRBP)
Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 192 amino acids (1-172 a.a.) and having a molecular mass of 20.8 kDa. CIRBP is fused to a 20 amino acid His-tag at N-terminus.
Purity: > 95.0% as determined by SDS-PAGE.
Formulation: CIRBP protein solution (0.5 mg/ml) containing 20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT, 50% glycerol and 0.1 M NaCl.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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