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Conditions of optimal CDKN2A Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Cyclin-dependent kinase inhibitors (CDKIs) are proteins that bind to and inhibit the activity of CDKs. Two major classes of CDK inhibitors have been identified. The p16 family (p15, p16, p18 and p19) binds to and inhibits the activities of CDK4 and CDK6. The p21 family (p21, p27, p28 and p57) can bind to broad range of CDK-cyclin complexes and inhibit their activities. CDKIs are capable of suppressing growth, and several lines of evidence strongly suggest that at least some CDKIs may be tumor suppressor proteins.
BP002504-PKA-341: Recombinant Human Cyclin-Dependent Kinase Inhibitor 2A (CDKN2A) Enzyme
Source: E. coli-derived.
A single non-glycosylated polypeptide chain containing 156 amino acids, approximately 16.5 kDa.
Purity: > 95.0% as determined by RP-HPLC and SDS-PAGE.
Formulation: CDKN2A was lyophilized from a concentrated (1 mg/ml) sterile solution containing 1x PBS pH-7.4.
Reconstitution: It is recommended to reconstitute the lyophilized Cyclin-dependent kinase in sterile water not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
CDKN2A Enzymes:
Recombinant Human Cyclin-Dependent Kinase Inhibitor 2A, TAT Enzyme
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