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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal CD86 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
CD86 type I membrane protein is a member of the immunoglobulin superfamily which is expressed by antigen-presenting cells, and acts as the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. CD86 binding with CD28 protein is a co-stimulatory signal for initiation of the T-cell. CD86 binding with CTLA-4 negatively regulates T-cell activation and diminishes the immune response.
PA005288-ANT-283: CD86 Monoclonal Antibody
Rat Monoclonal Antibody.
Applications: Blocking and staining antibody. For staining, use 10 ul/106 cells. Titer for blocking T cell activation should be determined by the investigator.
Reactivity: Mouse.
Immunogen: Purified mouse LPS-activated B cells.
Purification: Protein-A.
Form of Antibody: 1ug/ml in PBS (after reconstitution).
Clone: mB7-2.
Isotype: Rat IgG2a.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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