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Introduction
CD14 (also known lipopolysaccharide (LPS) receptor) is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation. CD14 has been shown to bind apoptotic cells.
PA005310-ANT-252: Biotin Conjugated CD14 Monoclonal Antibody
Mouse Monoclonal Antibody.
Applications: For staining, use 10 ul/106 cells.
Reactivity: Human.
Immunogen: Purified human B Cells Ig SubclassMouse IgG1.
Purification: Ion exchange column.
Form of Antibody: 1ug/ml in PBS (after reconstitution).
Clone: hCD4.
Isotype: Mouse IgG1.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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