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Conditions of optimal CCNB1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
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Or leave a message with a formal purchase
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Introduction
Cyclin B1 (CCNB1) is a regulatory protein involved in mitosis. CCNB1 creates a complex with p34(cdc2) to form the maturation-promoting factor (MPF). CCNB1 is vital for the control of the cell cycle at the G2/M (mitosis) transition. CCNB1 builds up steadily during the G2 and is immediately destroyed at mitosis. The 2 alternative transcripts produce a constitutively expressed transcript and a cell cycle-regulated transcript which is expressed predominantly during G2/M phase. These transcripts are a result of alternate transcription initiation sites.
BP002494-PKA-037: Recombinant Human Cyclin-B1 (CCNB1) Protein
Source: E. coli-derived.
A single polypeptide chain containing 457 amino acids (1-433) and having a molecular mass of 50.9 kDa. CCNB1 is fused to a 24 amino acid His-tag at N-terminus.
Purity: > 80% as determined by SDS-PAGE.
Formulation: The CCNB1 solution (0.25 mg/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 150 mM NaCl and 10% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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