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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal CCL3L1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
C-C Motif Chemokine 3-Like 1 (CCL3L1) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL3L1 is a ligand for CCR1, CCR3 and CCR5. CCL3L1 binds to several chemokine receptors including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The processed form LD78-beta (3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. The copy number of this gene varies among individuals: most individuals have 1-6 copies in the diploid genome, although rare individuals have zero or more than six copies. The human genome reference assembly contains two full copies of the gene (CCL3L3 and CCL3L1) and a partial pseudogene. This record represents the more centromeric full-length gene.
BP000292-CHM-263: Recombinant Human C-C Motif Chemokine 3-Like 1 (CCL3L1) Protein
Source: E. coli-derived.
A single, non-glycosylated, polypeptide chain containing 70 amino acids and having a molecular mass of 7.7 kDa.
The biological activity was determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 ug/ml.
Purity: > 97% by RP-HPLC and SDS-PAGE.
Formulation: Lyophilized from a 0.2 um filtered concentrated solution in 1xPBS, pH 7.4.
Reconstitution: It is recommended to reconstitute the lyophilized CCL3L1 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other CCL3L1 Proteins:
Recombinant Human CCL3L1 Protein
Recombinant Human CCL3L1 Protein, His Tag
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