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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal BMPR1A Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
BP000068-CYT-713: Recombinant Human Bone Morphogenetic protein Receptor-1A HEK
Source: HEK293-F Cells-derived.
A single, glycosylated, polypeptide chain containing 369 amino acids with a molecular weight of 43.7 kDa.
The biological activity of human BMPR1A is determined by its ability to inhibit human BMP-4 induction of alkaline phosphatase in the mouse chondrogenic cell line ATDC5. The observed ED50 range is from 0.1 to 0.3 ug/ml in the presence of 30 ug/ml of recombinant human BMP-4 protein.
Purity: > 95%, by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized from a 0.2 um filtered solution containing no additives or preservatives.
Reconstitution: It is recommended to reconstitute the lyophilized BMPR1A in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
BMPR1A Antibody:
BMPR1A Polyclonal Antibody
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