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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal BMP 4 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
BP000065-CYT-081: Recombinant Human Bone Morphogenetic protein-4 (BMP4), Active Protein
Source: HEK-derived.
A glycosylated disulfide linked homodimer, having a total molecular weight of 34 kDa. The BMP-4 is purified by proprietary chromatographic techniques.
The specific activity was determined by the dose dependent induction of alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line) and is typically 2-10 ug/ml.
Purity: > 95% as obsereved by SDS-PAGE.
Formulation: The BMP4 was lyophilized from 1 ug/ml in 1xPBS.
Reconstitution: It is recommended to reconstitute the lyophilized BMP-4 in sterile water not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other BMP 4 Protein:
Recombinant Human BMP4
BMP4 Antibody:
BMP4 Polyclonal Antibody
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