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Conditions of optimal BDNF Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.
BP001000-C076: Recombinant Human Brain-Derived Neurotrophic Factor (BDNF) Protein
Source: E. coli-derived.
Recombinant Human Brain-Derived Neurotrophic Factor (BDNF) Protein is a non-covalently linked homodimer with a molecular mass of 27 kD.
N-terminal sequence analysis: Met-His-Ser-Asp-Pro.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: Lyophilized aliquots with a 0.2 um filtered protein solution containing 20 mM PB pH8.0, 150 mM NaCl.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other BDNF Proteins:
Recombinant Human BDNF Protein
BDNF Antibodies:
BDNF Polyclonal Antibody
BDNF Monoclonal Antibody
BDNF ELISA Kits:
Rat BDNF ELISA Kit
Mouse BDNF ELISA Kit
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