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BCL2L2 Protein

Bcl-2-like protein 2, Bcl2-L-2, Apoptosis regulator Bcl-W, BCLW, KIAA0271, B-Cell Lymphoma Protein 2

Catalog No. Product Name Size List Price (US$) Quantity
BP001239-PRO-768 Recombinant Human BCL2L2 Protein 25 ug 160.00
BP001239-PRO-768 Recombinant Human BCL2L2 Protein 1 mg 2250.00
Description

Introduction
Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in the brain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone-induced apoptosis. Furthermore, BCL2L2 mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.

BP001239-PRO-768: Recombinant Human Bcl-2-like protein 2 (BCL2L2)

Source: E. coli-derived.
Recombinant Human BCL2L2 is a single, non-glycosylated polypeptide chain containing 192 amino acids (1-172 a.a.) and having a molecular weight of 20.9 kDa. The BCL2L2 is fused to a 20 a.a His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Predicted molecular mass: 20.9 kDa.
Purity: > 95.0% by SDS-PAGE.
Formulation: The BCL2L2 protein solution contains 20 mM Tris-HCl, pH-8, 100 mM NaCl and 10% glycerol.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

Other BCL2L2 Proteins:
Recombinant Human BCL2L2 Protein

BCL2L2 Antibodies:
BCL2L2 Polyclonal Antibody

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