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Conditions of optimal BAALC Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
BAALC gene is found in patients with acute myeloid leukemia and is conserved among mammals and is not found in lower organisms. Tissues which express BAALC develop from the neuroectoderm. BAALC is located both in the membrane and in the cytoplasma, it exists as multiple alternatively spliced isoform. BAALC is expressed by hematopoetic and neural cells, BAALC interacts with CaMKII? and is involved in synaptic function at postsynaptic lipid rafts. Overexpression of BAALC concomitant forecast adverse clinical outcome and defines a significant risk factor in cytogenetically normal acute myeloid leukemia (AML).
BP003029-PRO-758: Recombinant Human Brain and acute leukemia cytoplasmic protein (BAALC) protein
Source: E. coli-derived.
Recombinant Human Brain and acute leukemia cytoplasmic protein (BAALC) protein is fused to a 20 amino acid His Tag at N-terminus and purified by standard chromatogrpahy techniques.
Predicted molecular mass: 17.7 kDa.
Purity: > 95.0% by SDS-PAGE.
Formulation: The protein solution contains 20 mM Tris buffer pH-8, 1 mM DTT, 20% glycerol and 2 mM EDTA.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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