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Conditions of optimal ATF1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
ATF1, a cyclic-AMP dependent transcription factor, is expressed in a large selection of cell types and can dimerize with CREB. MSK1 and MSK2 protein kinases are essential for the stress-induced phosphorylation of transcription factors CREB and ATF1 in primary embryonic fibroblasts. Epidermal growth factor induction of c-jun expression needs ATF1 and MEF2 sites in the c-jun promoter.
BP002481-PKA-019: Recombinant Human Activating Transcription Factor-1 (ATF1) Protein
Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 295 amino acids (1-271 and having a molecular mass of 31.8 kDa. ATF1 is fused to a 24 amino acid His-tag at N-terminus.
Purity: > 90% as determined by SDS-PAGE.
Formulation: The ATF1 solution (0.25 mg/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 200 mM NaCl, 5 mM DTT, 2 mM EDTA and 50% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
ATF1 Antibodies:
ATF1 Polyclonal Antibody
ATF1 (Phospho-Ser63) Polyclonal Antibody
ATF1 (Ab-63) Polyclonal Antibody
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