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Conditions of optimal ARL14 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
ADP-ribosylation factor-like 14 (ARL14) is a developmentally regulated member of the ADP-ribosylation factor/ARF-like protein (ARF/ARL) family of Ras-related GTPases. ARL14 is GTPase which recruits MYO1E to MHC class II-containing vesicles via the effector protein C11orf46/ARF7EP and thus controls the movement of these vesicles along the actin cytoskeleton in dendritic cells. MHC-II transport was controlled by the GTPase ARL14/ARF7, which recruits the motor myosin 1E via an effector protein ARF7EP.
BP001808-PRO-936: Recombinant Human ADP-Ribosylation Factor-Like 14 (ARL14) Protein
Source: E. coli-derived,
Recombinant Human ARL14 is a single, non-glycosylated polypeptide chain containing 212 amino acids (1-192 a.a.) and having a molecular mass of 23.8 kDa (Molecular weight on SDS-PAGE will appear higher). ARL14 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Predicted molecular mass of 23.8 kDa.
Purity: > 90.0% by SDS-PAGE.
Formulation: ARL14 protein solution (0.25 mg/ml) containing 20 mM Tris-HCl buffer (pH 8.0), 2 mM DTT, 40% glycerol, 200 mM NaCl and 1 mM EDTA.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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