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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal APC Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Activated Protein C exerts an antithrombotic effect by inhibiting Factors Va and VIIIa.
In vitro data indicate that Activated Protein C has indirect profibrinolytic activity through its ability to inhibit plasminogen activator inhibitor-1 (PAI-1) and limiting generation of activated thrombin-activatable-fibrinolysis-inhibitor. Additionally, in vitro data indicate that Activated Protein C may exert an anti-inflammatory effect by inhibiting human tumor necrosis factor production by monocytes, by blocking leukocyte adhesion to selectins, and by limiting the thrombin-induced inflammatory responses within the microvascular endothelium.
BP000691-ENZ-349: Recombinant Human Activated protein C cofactor (APC)
Source: Chinese Hamster Ovary Cells (CHO)-derived.
A disulfide-linked homodimeric, glycosylated, polypeptide chain having a molecular mass of 55 kDa. A serine protease with the same amino acid sequence and glycosilation sites as the human plasma-derived Coagulation Factor V.
Purity: > 99%, by RP-HPLC and SDS-PAGE.
Formulation: Each mg protein contains 7.6 mg sodium chloride, 1.5 mg citrate and 6 mg sucrose.
Reconstitution: It is recommended to reconstitute the lyophilized Coagulation factor V in sterile 18 MΩ-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other APC Antibodies:
APC Polyclonal Antibody
APC Monoclonal Antibody
APC Monoclonal Antibody
APC (Phospho-Ser2054) Polyclonal Antibody
APC (Ab-2054) Polyclonal Antibody
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