The most comprehensive hybridoma-based mouse monoclonal antibody production services: custom production of monoclonal antibodies against non-modified, phospho-specific, methylation-specific, and acetylation-specific peptides and proteins as well as small molecular compounds; for ELISA, Western blot, IHC, and flow cytometry applications.
The lowest custom mouse monoclonal antibody production price: $6000.
Fast turnaround: 24 weeks once the antigen is available.- Any gene;
- Any host cell, including primary cell;
- Highly efficient and precise.
Fast turnaround:
Knock-out cell line generation: 16-19 weeks.
Knock-in cell line generation: 20-24 weeks.The most comprehensive murine hybridoma generation for therapeutic antibody services:
Genetic background: white, black, immunodeficiency, knock-out, and humanized mice; rat; hamster;
Antigens: proteins, peptides, DNA, cells expressing certain proteins.
All are done in US.
Experienced scientists working on antibody and cell line development services for decades. >90% success rate of stable cell line generation.
Stable cell lines developed with our proprietary recombinant antibody expression system with multiple selectable markers is very productive in expressing target proteins.
Fast turnaround:
Basic service: 7-8 weeks.
Premium service: 12-14 weeks.
Pool cells: 6 weeks.Experienced scientists working on antigen and antibody production, antibody engineering, lentivirus, and cell line development services for decades. >90% success rate of stable cell line generation.
Fast turnaround:
Antigen (peptide or protein) production: 3-6 weeks.
Mouse monoclonal antibody production: 20-24 weeks.
Screening phage or yeast libraries for fully human antibodies: 8-12 weeks.
Sequencing hybrioma antibody: 1-3 weeks.
Chimeric antibody production: 3-4 weeks.
Antibody humanization: 8-10 weeks.
Construction of CAR cassette, lentivirus packaging and production: 4-5 weeks.
T-cell activation, transduction, and CAR T-cell expansion: 4-5 weeks.
Confirmation of CAR expression, IFN-gamma ELISA, and cytotoxicity assay of transduced and expanded T-cells: 2 weeks.While the success rate of stable cell line generation is highly dependent on the target genes and Syd Labs can not guarantee 100% success rate, our in-house data show a success rate greater than 90%.
Fast turnaround of stable cell line development: 6-7 weeks.
We have a lot of experience in dealing with difficult-to-express proteins.- Any gene;
- Any host cell, including primary cell;
- Significantly improved efficiency of changing protein expression level compared to non-viral DNA transfection methods.
Fast turnaround:
Clonal stable cell line generation: 12-14 weeks.
Cell pool generation: 8-10 weeks.Experienced scientists working on protein engineering, expression, and purification, and cell line development services for decades. >90% success rate of stable cell line generation.
Stable cell lines developed with our proprietary protein expression system with multiple selectable markers is very productive in expressing target proteins.
Fast turnaround:
1 week for synthesizing a gene for expressing the target protein.
1 week for molecular construction of the gene.
5-6 weeks for generation of suspension CHO stable cell lines expressing the target protein.
5-6 weeks for additional services included in the premium package.C003: Humira Biosimilar Stable Cell Line (CHO)
The yield of Humira biosimilar from the CHO stable cell line was above 2.0 g/L in a 50 liter manufacturing.
C005: Lucentis Biosimilar Cell Line (E. coli)
The yield of Lucentis biosimilar from E.coli was above 36 mg/L in a 7.5 liter manufacturing.