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Conditions of optimal Ang K1-3 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Ang K1-3 is a proteolytic fragment of plasminogen containing the first three kringle structures. A specific inhibitor of endothelial cell growth and angiogenesis. More active relative to kringles 1-4. Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth.
BP002115-PRO-284: Recombinant Human Angiostatin Kringles 1-3 Human (Ang K1-3) Protein
Source: E. Coli-derived.
Recombinant Human Angiostatin Kringles 1-3 Human (Ang K1-3) protein is a single, non-glycosylated polypeptide chain containing 259 amino acids and having a molecular mass of approximately 30.0 kDa. The Ang K1-3 is purified by proprietary chromatographic techniques.
The specific activity of Ang K1-3 protein is assayed on anti-proliferation and anti-migration of endothelial cells in vitro and anti-angiogenesis in vivo. The specific activity of anti-migration of endothelial cells in vitro is 55,000 Units/mg.
Purity: > 95.0% as determined by analysis by RP-HPLC and SDS-PAGE.
Formulation: Lyophilized from a 0.2 um filtered concentrated (1.0 mg/ml) solution in 20 mM NaAc, pH 5.5, 4% mannitol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Angiostatin K1-3 Antibodies:
Angiostatin K1-3 Polyclonal Antibody
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