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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal AGER Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Advanced Glycosylation End Product-Specific Receptor (AGER) belongs to the immunoglobulin superfamily of cell surface molecules. It lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Besides AGEs, AGER is also able to bind other ligands which is thought to result in pro-inflammatory gene activation. It is known that AGER serve as a mediator of both acute and chronic vascular inflammation in certain conditions such as atherosclerosis and in particular as a complication of diabetes. Furthermore, it plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes.
BP001717-PRO-601: Recombinant Human Advanced Glycosylation End Product-Specific Receptor (AGER) Protein, HEK
Source: HEK 293-derived.
Recombinant Human Advanced Glycosylation End Product-Specific Receptor (AGER) Protein is a single, glycosylated, polypeptide chain containing 331 amino acids and having a molecular mass of 35.2 kDa. sRAGE Human is fused to Flag tag at C-Terminus. sRAGE Human is purified by proprietary chromatographic techniques.
Purity: > 95% by SDS-PAGE.
Formulation: The sterile filtered concentrated (0.5 mg/ml) protein solution was lyophilized with 50 mM Tris-HCl pH 7.5 & 50 mM NaCl.
Reconstitution: Add deionized water to a working concentration of 0.5 mg/ml and let the lyophilized pellet dissolve completely.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other AGER Proteins:
Recombinant Human AGER Protein
Recombinant Human AGER Protein
AGER Antibodies:
AGER Polyclonal Antibody
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