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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal AES Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Amino-terminal enhancer of split (AES) is a member of the groucho/TLE family of proteins. AES can function as a homooligomer or as a heteroologimer with other family members in order to forcefully repress the expression of other family member genes. Furthermore, AES can repress NFkB-regulated gene expression and is believed to have a significant role in initiating and maintaining cell differentiation events. AES is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein which is involved in neurogenesis during embryonic development. The AES protein is expressed predominately in the fetal brain, liver, lung, heart and kidney and also in the adult muscle.
BP002107-PRO-169: Recombinant Human Amino-Terminal Enhancer of Split (AES) Protein
Source: E. Coli-derived.
Recombinant Human Amino-Terminal Enhancer of Split (AES) Protein is a single, non-glycosylated, polypeptide chain containing 217 amino acids (1-197 a.a.) and having a molecular mass of 24.1 kDa. The AES is purified by proprietary chromatographic techniques.
Purity: > 95.0% as determined by SDS-PAGE.
Formulation: The AES solution (1 mg/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT and 20% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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