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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal ACVR1B Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
ACVR1B on ligand binding, creates a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. ACVR1B Phosphorylates TTRAP.
BP000823-PKA-366: Recombinant Human Activin A Receptor, Type IB
Source: HEK293 Cells-derived.
A single, glycosylated, polypeptide chain having a molecular weight of 38.2 kDa though on SDS-PAGE migrates at about 46 kDa due to the glycosilation.
In a functional ELISA, immobilized recombinant Human ACVR1B (0.2 ?g/mL) will bind recombinant Human ACVR1B with a linear range of 0.8?00 ug/ml.
Purity > 95% by SDS-PAGE.
Formulation: Lyophilized from a 0.2 um filtered solution containing no additives or preservatives.
Reconstitution: It is recommended to reconstitute the lyophilized ACVR1B in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
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