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ABO Enzyme

Histo-blood group ABO system transferase, Fucosylglycoprotein 3-alpha-galactosyltransferase, NAGAT, GTB, A3GALNT, A3GALT1

Catalog No. Product Name Size List Price (US$) Quantity
BP002789-ENZ-167 Recombinant Human Histo-blood group ABO system transferase Enzyme 10 ug 160.00
BP002789-ENZ-167 Recombinant Human Histo-blood group ABO system transferase Enzyme 1 mg 5200.00
Description

Introduction
NAGAT (ABO) is a member of the glycosyltransferase 6 family. The ABO protein is the basis of the ABO blood group system and related to the first discovered blood group system, ABO. The allele that is present in an individual determines the blood group. The histo-blood group ABO is comprised of 3 carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity which converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals are deficient of such activity.

BP002789-ENZ-167: Recombinant Human Histo-blood group ABO system transferase (ABO) Enzyme

Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 322 amino acids (54-354 a.a) and having a molecular mass of 37.4 kDa. ABO is fused to a 21 amino acid His-tag at N-terminus.
Purity: > 85.0% as determined by SDS-PAGE.
Formulation: ABO protein solution (0.5 mg/ml) containing 20 mM Tris-HCl buffer (pH 8.0), 2 mM DTT, 20% glycerol and 200 mM NaCl.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

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