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FGFR2 Antibody

Fibroblast Growth Factor-Receptor 2 Antibody, Fibroblast Growth Factor Receptor 2 Antiboy

Catalog No. Product Name Size List Price (US$) Quantity
PA000172-PA1241 FGFR2 Polyclonal Antibody 100 ug 350.00
Description

Background

Fibroblast growth factor receptor 2 (FGFR2) is a receptor for fibroblast growth factor encoded on a gene residing on chromosome 10. FGFR2 has also been designated as CD332. FGFR2 is a membrane-spanning tyrosine kinase that serves as a high affinity receptor for several members of the fibroblast growth factor (FGF) family. Its signals are absolutely required for vertebrate limb induction and that an FGFR2 signal is essential for the reciprocal regulation loop between FGF8 and FGF10 during limb induction.1 FGFR2 contributes to the outgrowth, differentiation, and maintenance of the inner cell mass and raise the possibility that this activity is mediated by FGF4 signals transmitted by FGFR2. The role of early FGF signaling in pregastrulation development as a possible adaptation to mammalian (amniote) embryogenesis is discussed.2.

PA000172-PA1241: FGFR2 Polyclonal Antibody

Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Human, rat, mouse. No cross reactivity with other proteins.
Applications: WB 0.1-0.5 ug/ml IHC-P 0.5-1 ug/ml.
Reactivity: Human, Mouse, Rat.
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human FGFR2, identical to the related rat and mouse sequence.
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Isotype: Rabbit IgG.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

Other FGFR2 Antibody:
FGFR2 Polyclonal Antibody

FGFR2 Protein:
Recombinant Human FGFR2 Fc Chimera

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