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Background Information:
An inhibitor of all known vascular endothelial growth factor receptor (VEGFR) kinases, and at high concentration, it also inhibits other tyrosine kinases such as PDGFR, c-Kit and c-FMS.
Reference:
1. K?osowska-Ward?ga A, Hasumi Y, et al., Combination therapy using imatinib and vatalanib improves the therapeutic efficiency of paclitaxel towards a mouse melanoma tumor. Melanoma Res. 2010 Oct 21. [Epub ahead of print].
APIM050253: VATALANIB
CAS No.: 212141-54-3.
Molecular Formula: C20H15ClN4 ? 2HCl.
Molecular Weight: 419.7.
Purity: >99% (HPLC).
QC: 1HNMR, HPLC.
Solubility: Soluble in water.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.
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