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uPA Enzyme

Urokinase-Type Plasminogen Activator, U-Plasminogen Activator, PLAU

Catalog No. Product Name Size List Price (US$) Quantity
BP000673-C393 Recombinant Human uPA Enzyme 10 ug 180.00
BP000673-C393 Recombinant Human uPA Enzyme 50 ug 528.00
BP000673-C393 Recombinant Human uPA Enzyme 1 mg 2640.00
Description

Introduction
Recombinant Human Urokinase-Type Plasminogen Activator is a serine protease, which specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. Urokinase-Type Plasminogen Activator is a potent marker of invasion and metastasis in many human cancers associated with breast, colon, stomach, bladder, brain, ovary and endometrium. Human Urokinase-Type Plasminogen Activator is initially synthesized as 431 amino acid precursor with a N-terminal signal peptide residues. The single chain molecule is processed into a disulfide-linked two-chain molecule. There exists two forms A chain, the long A chain contains an EGF-like domain that is responsible for binding of the uPA receptor. The B chain corresponds to the catalytic domain.

BP000673-C393: Recombinant Human Urokinase-Type Plasminogen Activator (uPA) Enzyme

Source: HEK 293-derived.
Recombinant Human Urokinase-Type Plasminogen Activator (uPA) Enzyme is expressed with sequence (Ser21-Leu431) of Human PLAU fused with a poly-histidine tag at the C-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: 0.2 um filtered solution of 20 mM HEPES, 150 mM NaCl, 2 mM CaCl, 10% Glycerol, pH 7.5.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

uPA Antibodies:
uPA Polyclonal Antibody

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