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TNFRSF11B Protein

Tumor Necrosis Factor Receptor Superfamily Member 11B, Osteoclastogenesis Inhibitory Factor, Osteoprotegerin, OCIF, OPG

Catalog No. Product Name Size List Price (US$) Quantity
BP000051-C325 Recombinant Human TNFRSF11B Protein 10 ug 98.00
BP000051-C325 Recombinant Human TNFRSF11B Protein 50 ug 144.00
BP000051-C325 Recombinant Human TNFRSF11B Protein 1 mg 1320.00
Description

Introduction
Osteoprotegerin (OPG) also known as Osteoclast Inhibiting Factor (OCIF) or Osteoclast Binding Factor (OBF), is a key factor inhibiting the differentiation and activation of osteoclasts, and is therefore essential for bone resorption (1-3). Osteoprotegerin is a glycoprotein belonging to the TNF receptor family. As a so called soluble "decoy" receptor, Osteoprotegerin inhibits the binding of RANK to RANKL and thus inhibits the recruitment, proliferation and activation of osteoclasts (4).

BP000051-C325: Recombinant Human Tumor Necrosis Factor Receptor Superfamily Member 11B (TNFRSF11B) Protein

Source: HEK 293-derived.
Recombinant Human Tumor Necrosis Factor Receptor Superfamily Member 11B (TNFRSF11B) Protein is expressed with sequence (E22-L401) of Human TNFRSF11B fused with a polyhistidine tag at the C-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 EU/ug).
Formulation: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

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