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TBP Antibody

TATA binding factor, TATA sequence-binding protein, TATA-box binding protein, TATA-box factor, TFIID

Catalog No. Product Name Size List Price (US$) Quantity
PA003493-PA1534 TBP Polyclonal Antibody 100 ug 350.00
Description

Introduction
TBP, TATA-binding protein, is a general transcription factor that binds specifically to a DNA sequence called the TATA box. The TBP gene is mapped to 6q27. This DNA sequence is found about 35 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP, along with a variety of TBP-associated factors, make up the TFIID, a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitiation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20% of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II.

PA003493-PA1534: TBP Polyclonal Antibody

Rabbit Polyclonal Antibody.
Applications: WB: 0.1-0.5 ug/ml.
Reactivity: Human, Mouse, Rat.
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human TBP, identical to the related rat and mouse sequences.
Purification: Immunogen affinity purified.
Form of Antibody: Lyophilized.
Isotype: Rabbit IgG.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

Other TBP Antibody:
TBP Polyclonal Antibody

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