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Conditions of optimal STAT6 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Signal Transducer and Activator of Transcription 6 (STAT6) is a member of the STAT family of transcription factors. At least seven STATs exist: STAT1, 2, 3, 4, 5a, 5b, and 6. They are responsible for an array of cellular activities including regulating growth, survival, differentiation, motility, and the immune response. STAT6 plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. STAT6 has been shown to interact with EP300, CREB-binding protein, NFKB1, Nuclear receptor coactivator 1, IRF4 and SND1.
BP002650-CG37: Recombinant Human Signal Transducer and Activator of Transcription 6 (STAT6) Protein
Source: E. coli-derived.
Recombinant Human Signal Transducer and Activator of Transcription 6 (STAT6) Protein is expressed with sequence (Ser627-Ser837) of Human STAT6 fused with a 6His tag at the C-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: 0.2 um filtered solution of PBS, pH 7.4.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
STAT6 Antibodies:
STAT6 Polyclonal Antibody
STAT6 Polyclonal Antibody
STAT6 (Phospho-Tyr641) Polyclonal Antibody
STAT6 (Phospho-Thr645) Polyclonal Antibody
STAT6 (Ab-645) Polyclonal Antibody
STAT6 (Ab-641) Polyclonal Antibody
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