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SPP1 Protein

Secreted Phosphoprotein 1, Uropontin, SPP-1, BNSP, OPN, Urinary Stone Protein, Bone Sialoprotein 1, Nephropontin

Catalog No. Product Name Size List Price (US$) Quantity
BP000239-C544 Recombinant Human SPP1 Protein 10 ug 98.00
BP000239-C544 Recombinant Human SPP1 Protein 50 ug 192.00
BP000239-C544 Recombinant Human SPP1 Protein 1 mg 2640.00
Description

Introduction
Osteopontin is a glycoprotein that was first identified in osteoblasts and is involved in bone remodeling, immune functions in fibroblasts, macrophages, and lymphocytes during inflammation and wound healing. SPP1 binds tightly to hydroxyapatite. SPP1 forms an integral part of the mineralized matrix. SPP1 is vital to cell-matrix interaction.
Secreted Phosphoprotein-1 protects against cardiac ischemia-reperfusion injury via late preconditioning. Expression of both Ostepontin and CD44 in hepatocellular carcinoma is linked with advanced tumor stage and contributes to prognosis information. SPP1 is the most over-expressed gene in intrahepatic cholangiocarcinoma. Secreted Phosphoprotein-1 overexpression is related with interstitial lung diseases.

BP000239-C544: Recombinant Human Secreted Phosphoprotein 1 (SPP1) Protein

Source: HEK 293-derived.
Recombinant Human Secreted Phosphoprotein 1 (SPP1) Protein is a secreted protein with sequence (Ile17-Asn314) of Human SPP1 fused with a polyhistidine tag at the C-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 EU/ug).
Formulation: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other SPP1 Proteins:
Recombinant Human SPP1 Protein, HEK
Recombinant Human SPP1 Protein

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