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Conditions of optimal SOX2 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
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Introduction:
Recombinant Human Sex determining region Y box 2 (Sox2) belongs to a diverse family of structurally-related transcription factors whose primary structure contains a high mobility group box domain. SOX2 is one of the important transcription factors required in induced pluripotent stem cells. SOX2 regulates the expression of multiple genes involved in embryonic development, including FGF-4, YES-1, ZFP206. SOX2 may as a switch in neuronal development, keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. It has been shown SOX2 can interact with PAX6.
BP001110-C408: Recombinant Human Sex determining region Y box 2 (SOX2) protein
Source: E.coli-derived.
Purity: > 95%, by reducing SDS-PAGE and SEC-HPLC.
Endotoxin: Less than 0.1 ng/ug (1 EU/ug).
Formulation: Lyophilized at 1 ug/ml in 20 mM PBS.
Reconstitution: It is recommended to reconstitute the lyophilized Recombinant Human Sox2-polyR in PBS not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
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