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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal SMAD4 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Background
SMAD4 plays a pivotal role in signal transduction of the transforming growth factor beta superfamily cytokines by mediating transcriptional activation of target genes. Smad4 signalling in T cells is required for suppression of gastrointestinal cancer. Mutational inactivation of SMAD4 causes TGF-beta unresponsiveness and gave a basis for understanding the physiologic role of this gene in tumorigenesis. Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases.
PA000086-MA1089: Smad4 DPC4 Monoclonal Antibody
Mouse Monoclonal Antibody.
Specificity/Sensitivity: Human. No cross reactivity with other proteins.
Applications: Western blot: At 2-4 ug/ml with the appropriate system to detect Smad4 in cells and tissues.
Reactivity: Human.
Immunogen: Recombinant human Smad4 (DPC4).
Purification: Purified by the goat anti-mouse IgG affinity chromatography.
Form of Antibody: Lyophilized from 1.2% sodium acetate, with 2 mg BSA and 0.01 mg NaN3 as preservative.
Clone: IMD-89.
Isotype: Mouse IgG1.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Other SMAD4 Antibodies:
Smad4 Polyclonal Antibody
Smad4 Polyclonal Antibody
Smad4 Polyclonal Antibody
SMAD4 Proteins:
Recombinant Human SMAD4 protein
Recombinant Human SMAD4 protein
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