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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal sFRP3 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Secreted frizzled-related protein 3, also known as Frizzled-related protein 1, Frezzled, Fritz, FrzB-1 and FRZB, is a secreted protein which belongs to the secreted frizzled-related protein (sFRP) family. FRZB contains one FZ (frizzled) domain and one NTR domain. FRZB is highly expressed in placenta and heart, followed by brain, skeletal muscle, kidney and pancreas. It is also weakly detected in lung and liver. Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis and antagonist of Wnt8 signaling. FRZB also regulates chondrocyte maturation and long bone development. Defects in FRZB are a cause of female-specific osteoarthritis (OA) susceptibility.
BP001410-CA61: Recombinant Human sFRP3 (Secreted frizzled-related protein 3)
Source: HEK 293 derived.
Purity > 95%, by reducing SDS-PAGE and SEC-HPLC.
Endotoxin: Less than 0.1 ng/ug (1 EU/ug).
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
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