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PMM1 Enzyme

Phosphomannomutase 1, PMM 1, PMMH-22, PMMH22

Catalog No. Product Name Size List Price (US$) Quantity
BP000667-C249 Recombinant Human PMM1 Enzyme 10 ug 180.00
BP000667-C249 Recombinant Human PMM1 Enzyme 50 ug 528.00
BP000667-C249 Recombinant Human PMM1 Enzyme 1 mg 2640.00
Description

Introduction
Phosphomannomutase 1 (PMM1) is an enzyme involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. PMM1 catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for the synthesis of dolichol-phosphate-mannose, which is crucial for N-linked glycosylation and accordingly the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins. Additionally, PMM1 may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain.

BP000667-C249: Recombinant Human Phosphomannomutase 1 (PMM1) Enzyme

Source: E. coli-derived.
Recombinant Human Phosphomannomutase 1 (PMM1) Enzyme is expressed with sequence (Met1-Ala262) of Human PMM1 fused with a His tag at the C-terminus.
Purity: > 95% by reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: 0.2 um filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 1 mM DTT, pH 8.0.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

Other PMM1 Enzymes:
Recombinant Human PMM1 Enzyme

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